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Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors

✍ Scribed by Irina Semkova; Josef Krieglstein


Book ID
117330899
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
685 KB
Volume
30
Category
Article
ISSN
0165-0173

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Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motoneurons, and has no effective treatment. Experimental studies in rodents have shown that motoneurons respond to a variety of molecules including brain-derived neurotrophic factor (BDNF),