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Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells

✍ Scribed by Pineda, J R; Rubio, N; Akerud, P; Urbán, N; Badimon, L; Arenas, E; Alberch, J; Blanco, J; Canals, J M


Book ID
110039896
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
355 KB
Volume
14
Category
Article
ISSN
0969-7128

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to possess potent neurotrophic effects on dopaminergic (DA) neurons. We attempted the transplantation of encapsulated GDNF‐producing cells to generate a stable supply of GDNF in the brain to promote neuroprotective and re