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Neuroprotection by cord blood stem cells against glutamate-induced apoptosis is mediated by Akt pathway

✍ Scribed by Venkata Ramesh Dasari; Krishna Kumar Veeravalli; Kay L. Saving; Meena Gujrati; Dan Fassett; Jeffrey D. Klopfenstein; Dzung H. Dinh; Jasti S. Rao


Book ID
113812263
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
925 KB
Volume
32
Category
Article
ISSN
0969-9961

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re