Neurophysiology of Parkinson's disease: from basic research to clinical correlates
β Scribed by Diego Centonze; Paolo Calabresi; Patrizia Giacomini; Giorgio Bernardi
- Book ID
- 119608107
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 122 KB
- Volume
- 110
- Category
- Article
- ISSN
- 1388-2457
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π SIMILAR VOLUMES
Parkinson's disease (PD) is characterized by motor and nonmotor (cognitive and limbic) deficits. The motor signs of PD include hypokinetic signs such as akinesia/bradykinesia, rigidity and loss of normal postural reflexes, and hyperkinetic signs such as tremor. Dopamine depletion in the striatum is
## Abstract Depression is one of the most common nonmotor complications of Parkinson's disease (PD) and has a major impact on quality of life. Although several clinical factors have been associated with depression in PD, the relationship between depression and stage of illness as well as between de