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Neuropharmacological Effects of Low and High Doses of Repeated Oral Dexfenfluramine in Rats: A Comparison with Fluoxetine

✍ Scribed by S. Caccia; S. Confalonieri; A. Bergami; C. Fracasso; M. Anelli; S. Garattini


Book ID
114103435
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
289 KB
Volume
57
Category
Article
ISSN
0091-3057

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## Abstract **Scope:** Furan, a food contaminant formed during heat processing, induces hepatocellular tumors in rodents and high incidences of cholangiocarcinomas in rats even at the lowest dose (2 mg/kg b.w.) administered. Initial estimates suggested that human intake of furan may be as high as 3