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Neuropharmacokinetic and Dynamic Studies of Agmatine (Decarboxylated Arginine)

✍ Scribed by H OANH X. NGUYEN; CORY J. GORACKE-POSTLE; LORI L. KAMINSKI; AARON C. OVERLAND; ANDREW D. MORGAN; CAROLYN A. FAIRBANKS

Book ID
111478322
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
338 KB
Volume
1009
Category
Article
ISSN
0890-6564

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## Abstract ## BACKGROUND The polyamine system is a promising target for anticancer therapy. Ideally, an antineoplastic compound affecting this system should inhibit both ornithine decarboxylase and the polyamine transporter, and toxicity should be mild. Agmatine, decarboxylated L‐arginine, appear