Neuropeptides in the internal anal sphincter in neurogenic faecal incontinence
โ Scribed by C. T. M. Speakman; C. H. V. Hoyle; M. A. Kamm; M. M. Henry; R. J. Nicholls; G. Burnstock
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 859 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0179-1958
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๐ SIMILAR VOLUMES
## Abstract There is histological and functional evidence that the internal anal sphincter is abnormal in patients with idiopathic faecal incontinence. The in vitro responsiveness of the internal anal sphincter to nor adrenaline (an important sympathetic neurotransmitter) and electrical field stimu
Twenty-five (18%) of 140 incontinent patients and 6 (17%) of 35 normal controls showed episodes of spontaneous internal sphincter relaxation during 30 min multiport manometric and electromyographic recording under resting conditions. The episodes lasted at least 15 s and reduced the pressure in the