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Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line

✍ Scribed by B. Veronesi; J.D. Carter; R.B. Devlin; S.A. Simon; M. Oortgiesen


Book ID
114484830
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
217 KB
Volume
33
Category
Article
ISSN
0143-4179

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## Abstract Activation of the capsaicin receptor (VR1 or TRPV1) in bronchial epithelial cells by capsaicinoids and other vanilloids promotes pro‐inflammatory cytokine production and cell death. The purpose of this study was to investigate the role of TRPV1‐mediated calcium flux from extracellular s