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Neuropeptide Y as a partial agonist of the Y1 receptor

✍ Scribed by Renu Sah; Ambikaipakan Balasubramaniam; Michael S. Parker; Floyd Sallee; Steven L. Parker


Book ID
113585725
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
445 KB
Volume
525
Category
Article
ISSN
0014-2999

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First selective agonist of the neuropept
✍ Denise Zwanziger; Ilka BΓΆhme; Diana Lindner; Annette G. Beck-Sickinger πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 368 KB

## Abstract Selective NPY analogues are potent tools for tumour targeting. Their Y~1~‐receptors are significantly over‐expressed in human breast tumours, whereas normal breast tissue only expresses Y~2~‐receptors. The endogenous peptide consists of 36 amino acids, whereas smaller peptides are prefe