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Neuropeptide substance P improves water maze performance in aged rats

✍ Scribed by R. U. Hasenöhrl; J. P. Huston; T. Schuurman


Book ID
105515787
Publisher
Springer
Year
1990
Tongue
English
Weight
467 KB
Volume
101
Category
Article
ISSN
0033-3158

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Bilateral excitotoxic lesions of the nucleus basalis magnocellularis in rats were used along with testing in the water maze task to assess whether inhibition of acetylcholinesterase with physostigmine would reverse the lesion-induced impairment. Rats were lesioned bilaterally in stages using iboteni