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Neuropathological substrates and structural changes in late-life depression: the impact of vascular burden

✍ Scribed by Aikaterini Xekardaki, Micaela Santos, Patrick Hof, Eniko Kövari, Constantin Bouras, Panteleimon Giannakopoulos

Book ID
111981361
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
632 KB
Volume
124
Category
Article
ISSN
0001-6322

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## Background: Signal hyperintensities on magnetic resonance imaging in late-life depression are associated with treatment resistance and poor outcome. these lesions are probably vascular in origin and proposed sites for vascular damage include the dorsolateral prefrontal cortex (dlpfc) and anterio