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Neuropathological and molecular studies of spinocerebellar ataxia type 6 (SCA6)

✍ Scribed by Hidenao Sasaki; Hideaki Kojima; Ichiro Yabe; Kunio Tashiro; Takeshi Hamada; Hirofumi Sawa; Hiroaki Hiraga; K. Nagashima


Book ID
106075522
Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
289 KB
Volume
95
Category
Article
ISSN
0001-6322

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## Abstract SCA6 is a slowly progressive, late‐onset cerebellar ataxia due to a trinucleotide expansion in the __CACNA1A__ gene. We describe two unrelated cases that presented with Parkinsonism and cerebellar ataxia. One case was L‐dopa–responsive with a pattern of ^18^F‐dopa uptake similar to Park