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Neurons and neuronal systems involved in the pathophysiologies of Rett syndrome

✍ Scribed by Henry G. Dunn


Book ID
117545566
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
51 KB
Volume
23
Category
Article
ISSN
0387-7604

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The brain biopsy of a patient with Rett syndrome showed light microscopic evidence of white matter disease. Ultrastructurally, many neurons and oligodendroglia contained membrane-bound electron-dense inclusions with a distinct lamellar and granular substructure. This substructure suggests that part