Neurons and neurofibrillary tangles in the hippocampal cortex in familial and sporadic Alzheimer's disease
β Scribed by Kazuo Sasaki; Yuken Fukutani; Masami Mukai; Nigel J. Cairns; Kiminori Isaki
- Book ID
- 108957614
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 878 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0919-6544
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The cholinergic neurons located within the pedunculopontine nucleus (Ch5) of patients with Alzheimer's disease (AD; n = 15), Parkinson's disease (PD; n = 2), and neurologically normal (n = 6) subjects were visualized immunohistochemically using choline acetyltransferase, pharmacohistochemicalIy usin
Although formation of neurofibrillary tangles is a major pathological feature of Alzheimer's disease (AD), the neurotransmitter content of neurofibrillary tangle-bearing neurons has not been well characterized. We studied the hippocampus of 6 patients with pathologically verified AD and 6 control su