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Neuronal nitric oxide synthase(NNOS) is upregulated in superior mesenteric arteries in portal hypertensive rats

✍ Scribed by S.Y. Kwon; Y. Iwakiri; R.J. Groszmann


Book ID
117372514
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
321 KB
Volume
38
Category
Article
ISSN
0168-8278

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Increased nitric oxide (NO) release has been implicated in the pathogenesis of the hyperdynamic circulation in portal hypertension. NOS 3 (eNOS) causes NO release from the endothelium in response to physical stimuli, such as increased blood flow and shear stress. We evaluated the functional activity