Neuronal nitric oxide synthase (nNOS) immunoreactivity in the spinal cord of transgenic mice with G93A mutant SOD1 gene
β Scribed by Shoichi Sasaki; Hitoshi Warita; Koji Abe; Makoto Iwata
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 119 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0001-6322
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π SIMILAR VOLUMES
Autoradiography with the nitric oxide synthase (NOS) inhibitor ( 3 H)nitro-L-arginine ([ 3 H]L-NNA) was used to quantify NOS in cervical and lumbar spinal cord in normal and dystrophic mice. A single homogeneous population of binding sites was seen in all subregions of the gray matter in normal mice
## Abstract Nitric oxide (NO) is an essential messenger molecule in brain, where it is produced in neurons mostly by the activity of the neuronal isoform of nitric oxide synthase (nNOS). To understand the participation of the different isoforms of NOS in physiological functioning and in pathologica