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Neuronal gap junction coupling as the primary determinant of the extent of glutamate-mediated excitotoxicity

✍ Scribed by Belousov, Andrei B.; Fontes, Joseph D.


Book ID
121608740
Publisher
Springer
Year
2013
Tongue
English
Weight
496 KB
Volume
121
Category
Article
ISSN
1435-1463

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## Abstract We investigate the mechanisms underlying the redox switch/redox coupling hypothesis by characterizing the competitive consumption of glucose or lactate and the kinetics of pyruvate production in primary cultures of cortical neurons and astrocytes from rat brain. Glucose consumption was