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Neuronal estrogen receptor-α mediates neuroprotection by 17β-estradiol

✍ Scribed by Elzer, Joachim G; Muhammad, Sajjad; Wintermantel, Tim M; Regnier-Vigouroux, Anne; Ludwig, Jochen; Schütz, Günther; Schwaninger, Markus


Book ID
109871299
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
419 KB
Volume
30
Category
Article
ISSN
0271-678X

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## Abstract Estrogen provides neuroprotection against neurodegenerative diseases, including Parkinson's disease. Its effects may stem from interactions with neurons, astrocytes, and microglia. We demonstrate here in primary cultures of rat mesencephalic neurons that estrogen protects them from inju