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Neuronal death and GSK-3β: a tau fetish?

✍ Scribed by Mark P Mattson

Book ID
117343404
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
24 KB
Volume
24
Category
Article
ISSN
0166-2236

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## Abstract Intracellular neurofibrillary tangles, one of the characteristic hallmarks of Alzheimer's disease (AD), are mainly composed of hyperphosphorylated tau. The abnormal tau phosphorylation seems to be related to altered activity of kinases such as glycogen synthase kinase‐3β (GSK‐3β). Tau p