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Neuronal Cyclooxygenase-2 Activity and Prostaglandins PGE2, PGD2, and PGF2α Exacerbate Hypoxic Neuronal Injury in Neuron-enriched Primary Culture

✍ Scribed by Wenjin Li; Shasha Wu; Robert W. Hickey; Marie E. Rose; Jun Chen; Steven H. Graham

Book ID
106483816
Publisher
Springer
Year
2007
Tongue
English
Weight
410 KB
Volume
33
Category
Article
ISSN
0364-3190

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## Interleukin-1 beta (IL-1␤ ) is an inflammatory cytokine whose expression is elevated in brain during seizures, ischemia, and injury. Expression of IL-1␤ and its receptor can also be observed in normal brain. Platelet-activating factor (PAF) is also a dual mediator that promotes neuronal plastici