Neuronal cell loss accompanies the brain tissue response to chronically implanted silicon microelectrode arrays

The brain tissue response to implanted s

The brain tissue response to implanted silicon microelectrode arrays is increased when the device is tethered to the skull

✍ Roy Biran; Dave C. Martin; Patrick A. Tresco 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 712 KB

## Abstract The influence of tethering silicon microelectrode arrays on the cortical brain tissue reaction was compared with that of untethered implants placed in the same location by identical means using immunoflourescent methods and cell type specific markers over indwelling periods of 1–4 weeks