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Neuronal Apoptosis Induced by β-Amyloid Is Mediated by Caspase-8

✍ Scribed by Kathryn J. Ivins; Phillip L. Thornton; Troy T. Rohn; Carl W. Cotman

Book ID
115641503
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
485 KB
Volume
6
Category
Article
ISSN
0969-9961

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## Abstract β‐amyloid peptide (Aβ) has been implicated in the pathogenesis of Alzheimer disease and has been reported to induce apoptotic death in cell culture. Cysteine proteases, a family of enzymes known as caspases, mediate cell death in many models of apoptosis. Multiple caspases have been imp