Parvalbumin (a calcium-binding protein)-immunoreactive (PV-Ir) neurons in the cerebral cortex were examined in 20 postmortem brains obtained from elderly controls and patients with Pick's disease (PD). The type of PV-Ir neurons and their distribution in control and PD brains were similar. The number
✦ LIBER ✦
Neuronal and glial DNA fragmentation in Pick’s disease
✍ Scribed by A. M. Gleckman; Z. Jiang; Y. Liu; T. W. Smith
- Publisher
- Springer-Verlag
- Year
- 1999
- Tongue
- English
- Weight
- 258 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0001-6322
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Hippocampal atrophy and neuron loss are early and reproducible findings in Alzheimer's disease, and recent magnetic resonance imaging studies indicate that hippocampal atrophy may also be present in Parkinson's disease (PD). To determine whether or not cell loss occurs in PD, we estimated the total