High expression of disease-related Cln6
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Melanie Thelen; Susanne Fehr; Michaela Schweizer; Thomas Braulke; Giovanna Galli
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Article
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2011
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John Wiley and Sons
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English
⚖ 502 KB
## Abstract Mutations in the __CLN6__ gene cause a variant form of late infantile neuronal ceroid lipofuscinosis, a relentless neurodegenerative disease that is inherited as an autosomal recessive trait in humans and in the naturally occurring __nclf__ mouse strain. The CLN6 protein is localized in