Neuromyotonia and type I myofiber predominance in amyloidosis

✍ Scribed by Laurie Gutmann; Ludwig Gutmann; Sydney S. Schochet

• Book ID: 101254663
• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 371 KB
• Volume: 19
• Category: Article
• ISSN: 0148-639X
• DOI: 10.1002/(sici)1097-4598(199610)19:10<1338::aid-mus12>3.0.co;2-q

✦ Synopsis

A case of amyloidosis presented with neuromyotonia and marked predominance of type I myofibers as documented by biopsy of an enlarged anterior tibialis muscle. This likely represents conversion of type II fibers to type I from continuous neuromyotonic stimulation. This transformation is well described to occur in animal models and this case represents a unique human example. Enlarged muscles likely reflected pseudohypertrophy. 0 1996 John Wiley & Sons, Inc.