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Neuromuscular junction macromolecules in the pathogenesis of amyotrophic lateral sclerosis

โœ Scribed by Festoff, Barry W.


Book ID
122028769
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
767 KB
Volume
6
Category
Article
ISSN
0306-9877

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Amyotrophic lateral sclerosis: Serum fac
โœ Thomas J. O'Shaughnessy; Haidun Yan; Jimok Kim; Eric H. Middlekauff; Kwang W. Le ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 141 KB

Sera from 30 patients with sporadic amyotrophic lateral sclerosis (ALS) were tested to determine their effects at the neuromuscular junction. Spontaneous transmitter release was significantly increased, as evidenced by a 151% increase in MEPP frequency, by sera from 16 ALS patients. In addition, 16