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Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes

✍ Scribed by Li, Xi-Ming; Finnman, Ulla-Britt; von Euler, Gabriel; Hedlund, Peter B.; Fuxe, Kjell


Book ID
122037274
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
408 KB
Volume
155
Category
Article
ISSN
0304-3940

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N-0923, a selective dopamine D2 receptor
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## Abstract Certain aminotetralins are known to be potent dopamine D~2~ receptor agonists. N‐0923, [‐]2‐(N‐propyl‐N‐2‐thienylethylamino)‐5‐hydroxytetralin HCl, recognizes the high and low affinity states of the D~2~ receptor in membranes from bovine caudate with a K~low~ of 79 nM. The selectivity r