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Neurolymphomatosis—diagnosis and assessment of treatment response by FDG PET-CT

✍ Scribed by M Lin; J Kilanowska; J Taper; J Chu

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
81 KB
Volume
26
Category
Article
ISSN
0278-0232

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✦ Synopsis

Abstract

Neurolymphomatosis (NL) is lymphomatous infiltration of peripheral nerves, and is an uncommon manifestation of non‐Hodgkin's lymphoma (NHL). Although nerve biopsy is the main method for histological diagnosis, a blind nerve biopsy may not be diagnostic. While CT and MRI have been used to detect NL, recent reports demonstrated the benefit of integrated positron emission tomography (PET) using F^18^‐2‐fluoro‐2‐deoxy‐D‐glucose (FDG) combined with computed tomography (CT). We described the utility of FDG PET‐CT in this uncommon subgroup of NHL where it can assist in establishing the diagnosis, the potential to guide sites for biopsy and in the assessment of response to therapy. Copyright © 2007 John Wiley & Sons, Ltd.

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