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Neurological disorders: The alpha and beta of protein folding

✍ Scribed by López, Juan Carlos

Book ID
109964343
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
357 KB
Volume
3
Category
Article
ISSN
1471-0048

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## Abstract Most proteins encoded by the nuclear genome are synthesized in the cytoplasm and fold into precise 3D structures. During synthesis, the nascent polypeptide begins to fold as it traverses the large subunit of the ribosome and is assisted by molecular chaperones in attaining its precise f