Neuroleptic malignant syndrome in advanced Parkinson's disease
โ Scribed by P.H. Gordon; S.J. Frucht
- Book ID
- 102945043
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 720 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0885-3185
- DOI
- 10.1002/mds.1166
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โฆ Synopsis
Abstract
Neuroleptic malignant syndrome is a serious complication of levodopa withdrawal in patients with Parkinson's disease. We report a patient with advanced parkinsonism who developed neuroleptic malignant syndrome in the setting of inadequate levodopa intake. His symptoms improved with levodopa replacement, but dramatically worsened when enteral feeding was begun due to interference with intestinal absorption of levodopa. ยฉ 2001 Movement Disorder Society.
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## Abstract A case of neuroleptic malignant syndrome (NMS) in a patient with Parkinson's disease (PD) is presented. The syndrome was precipitated by the atypical antipsychotic, ziprasidone. The challenge of recognizing NMS in a patient with underlying parkinsonian symptoms, where prominent symptom