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Neuroleptic-induced acute and chronic akathisia: A clinical comparison

✍ Scribed by Jong-Hoon Kim; Young-Ho Jin; Ung Gu Kang; Yong Min Ahn; Kyoo-Seob Ha; Yong Sik Kim


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
56 KB
Volume
20
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

We compared the severity of subjective and objective symptomatology of akathisia between the acute and chronic subtypes of neuroleptic‐induced akathisia. Sixty‐one schizophrenic subjects were evaluated. Multivariate analysis revealed that motor manifestations and distress of akathisia were less severe in chronic akathisia than in acute akathisia. The severity of subjective restlessness was not significantly different between the two groups. In conclusion, there were differences in the severity of symptoms and signs between the acute and chronic subtypes of akathisia, suggesting that the severity of the subjective and objective components of akathisia may be differentially affected by the duration of akathisia. Β© 2005 Movement Disorder Society


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Neuroleptic induced akathisia is a common and distressful extrapyramidal side effect of antipsychotic treatment. A significant proportion of the variability of its development has been left unexplained and has to be attributed to individual susceptibility. Since hereditary factors have been discusse