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Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease

✍ Scribed by Annika Thorsell; Maria Bjerke; Johan Gobom; Eva Brunhage; Eugeen Vanmechelen; Niels Andreasen; Oskar Hansson; Lennart Minthon; Henrik Zetterberg; Kaj Blennow

Book ID
113505276
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
745 KB
Volume
1362
Category
Article
ISSN
0006-8993

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✍ Kajsa SΓ€mgΓ₯rd; Henrik Zetterberg; Kaj Blennow; Oskar Hansson; Lennart Minthon; E πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 237 KB

## Abstract ## Objectives The aim of this longitudinal study was to test the hypothesis that CSF biomarkers in AD patients also may be forward‐looking measures that are associated not only with the degree and profile of cognitive impairment but also with changes in cognition over time. ## Methods