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Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death

✍ Scribed by Subhadip Raychaudhuri; Joanna Skommer; Kristen Henty; Nigel Birch; Thomas Brittain


Publisher
Springer
Year
2009
Tongue
English
Weight
380 KB
Volume
15
Category
Article
ISSN
1360-8185

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## Abstract The Raf serine‐threonine kinase is upregulated in many human tumors and plays a pivotal role in tumor cell proliferation and survival. Abrogation of c‐Raf expression by specific antisense oligonucleotides (Raf‐AS‐ODN) efficiently blocks tumor cell growth and induces apoptosis in human c