Neurogenesis and depression: etiology or epiphenomenon?
β Scribed by Fritz A Henn; Barbara Vollmayr
- Book ID
- 119196418
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 87 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0006-3223
No coin nor oath required. For personal study only.
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## Abstract The transcription factor CREB has been implicated in signalling pathways relevant for pathogenesis and therapy of depression. CREB is upregulated and activated in the hippocampus by chronic antidepressant treatment, similarly as neurogenesis. Surprisingly, a recent study using CREBβdefi