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Neurofibromatosis type 2 with multiple primary brain tumors in monozygotic twins

โœ Scribed by Hironobu Harada; Yoshiaki Kumon; Nobuaki Hatta; Saburo Sakaki; Shinsuke Ohta

Book ID
117262215
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
383 KB
Volume
51
Category
Article
ISSN
0090-3019

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## Mutations in the neurofibromatosis 2 (NF2) tumor suppressor gene on chromosome 22q12 cause a clinically variable autosomal dominant syndrome characterized by bilateral vestibular schwannomas (VSs), other nervous system tumors, and early onset lenticular cataracts. We studied three pairs of mono