## Background: In the human prostate cancer cell line lncap, interleukin (il)-6 has been shown to regulate both growth and neuroendocrine (ne) differentiation. we recently observed that il-6 mediated growth arrest in lncap by activating stat 3. since differentiation and growth arrest are often asso
Neuroendocrine differentiation in prostate cancer
β Scribed by Jingwen Wang; Yang Yao
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 77 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1610-1979
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Neuroendocrine differentiation in prostate cancer has received much attention recently because it has been found to be associated with androgen independence and shortened patient survival in some studies. We have investigated the effect of the cytokines interleukin-1 (IL-1), IL-2, and IL-6 on the ex
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## Abstract Despite improvements in diagnosis of advanced prostate cancer (PCa), treatment is not efficient and 5βyear survival is still low. Initially, the less abundant of cell types, neuroendocrine cells (NE), are involved in regulatory process but their physiological role is not fully understoo
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