Neuroendocrine Differentiation in Prostate Cancer: Implications for New Treatment Modalities
β Scribed by Nadezda Vashchenko; Per-Anders Abrahamsson
- Book ID
- 113608777
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 279 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0302-2838
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π SIMILAR VOLUMES
## BACKGROUND. We studied the extent of neuroendocrine (NE) tumor cell differentiation and its relation to regressive changes in prostate cancer after 3-month hormonal treatment. METHODS. Radical prostatectomy specimens from 103 patients, randomized to 3-month neoadjuvant LH-RH-analogue treatment (
## Abstract Despite improvements in diagnosis of advanced prostate cancer (PCa), treatment is not efficient and 5βyear survival is still low. Initially, the less abundant of cell types, neuroendocrine cells (NE), are involved in regulatory process but their physiological role is not fully understoo