Neuroendocrine differentiation in prostate cancer: Current and emerging therapy strategies
โ Scribed by Conteduca, Vincenza; Aieta, Michele; Amadori, Dino; De Giorgi, Ugo
- Book ID
- 124106399
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 398 KB
- Volume
- 92
- Category
- Article
- ISSN
- 1040-8428
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๐ SIMILAR VOLUMES
Neuroendocrine differentiation in prostate cancer has received much attention recently because it has been found to be associated with androgen independence and shortened patient survival in some studies. We have investigated the effect of the cytokines interleukin-1 (IL-1), IL-2, and IL-6 on the ex
## BACKGROUND. We studied the extent of neuroendocrine (NE) tumor cell differentiation and its relation to regressive changes in prostate cancer after 3-month hormonal treatment. METHODS. Radical prostatectomy specimens from 103 patients, randomized to 3-month neoadjuvant LH-RH-analogue treatment (