Neuroendocrine and biologic features of primary tumors and tissue in pulmonary large cell carcinomas
✍ Scribed by Alexandre M Ab' Saber; Ledo Mazzei Massoni Neto; Cristina P Bianchi; Bruno B Ctenas; Edwin R Parra; Esmeralda M Eher; João Carlos Pereira; Teresa Takagaki; Nise H Yamaguchi; Vera L Capelozzi
- Book ID
- 116259531
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 350 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0003-4975
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## Abstract ## BACKGROUND. Poorly differentiated large cell neuroendocrine carcinomas (LCNEC) comprise a rare and still scarcely known subgroup of neuroendocrine tumors. The objective of this study was to investigate the epidemiology, clinical presentation, prognostic factors, and molecular pathwa
## BACKGROUND. Large cell neuroendocrine carcinoma (LCNEC) of the lung has been proposed as a new disease entity. To establish diagnostic features, bronchial brush cytologic findings were evaluated. ## METHODS. Bronchial brush cytology material of 20 LCNECs was evaluated by light microscopy and