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Neurodegenerative disease: Prion proteins take a knock

✍ Scribed by Whalley, Katherine


Book ID
109962731
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
133 KB
Volume
9
Category
Article
ISSN
1471-0048

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Transmissible spongiform encephalopathies (TSE) or "prion diseases" have been related to the "protein-only hypothesis", which suggests that the "scrapie form (PrP Sc )" of the prion protein (PrP) is the TSE infectious agent. The nmr structure of the ubiquitous benign cellular form of PrP (PrP C ) co