## Abstract Amyloid formation plays a central role in the cause and progression of Alzheimer's disease. The major component of this amyloid is the amyloid‐β (Aβ) peptide, which is currently the subject of intense study. This review discusses some recent studies in the area of Aβ synthesis, purifica
✦ LIBER ✦
Neurodegenerative disease: Amyloid-β and PrPC: it takes two
✍ Scribed by Whalley, Katherine
- Book ID
- 109962876
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 211 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1471-0048
- DOI
- 10.1038/nrn2633
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## Abstract The neuropathological features associated with Alzheimer's disease (AD) brain include the presence of extracellular neuritic plaques composed of amyloid β protein (Aβ), intracellular neurofibrillary tangles containing hyperphosphorylated tau protein, and the loss of basal forebrain chol