Evidence that 3-hydroxy-3-methylglutaric
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Guilhian Leipnitz; Bianca Seminotti; Josué Haubrich; Manuela B. Dalcin; Karina B
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Article
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2008
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John Wiley and Sons
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English
⚖ 342 KB
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## Abstract In the present work we investigated the in vitro effect of 3‐hydroxy‐3‐methylglutarate (HMG) that accumulates in 3‐hydroxy‐3‐methylglutaryl‐CoA lyase deficiency (HMGLD) on important parameters of oxidative stress in rat cerebral cortex. It was observed that HMG induced lipid peroxidatio