Resistance to extrapyramidal effects of
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Dr. G. M. De Montis; P. Devoto; D. Meloni; A. Porcella; P. Saba; A. Tagliamonte
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Article
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1989
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John Wiley and Sons
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English
โ 630 KB
Rats made tolerant to morphine show neither a change in brain opiate receptor number nor altered sensitivity to the inhibitory effect of opiates on striatal adenylate cyclase (AC) activity. Interestingly, SCH 23390, a selective blocker of D1 dopamine (DA) receptors which, given chronically to rats,