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Neurochemical changes in creutzfeldt-jakob disease

✍ Scribed by A. Federico; P. Annunziata; G. Malentacchi


Publisher
Springer
Year
1980
Tongue
English
Weight
807 KB
Volume
223
Category
Article
ISSN
0340-5354

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✦ Synopsis


A biochemical study of a case affected by Creutzfeldt-Jakob disease is reported. Changes were found in soluble and insoluble proteins, glycoproteins and mucopolysaccharides and in total lipids, glycolipids, phospholipids and gangliosides. Also CNPase, choline acetyltransferase, 5'-nucleotidase and several glycosidases have an altered activity. All these data give a complete neurochemical pattern of the changes underlying the morphological and functional alterations in this disease.


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