Neuroblastoma of suprarenal medullary anlage with metastasis to brain
✍ Scribed by Bela Halpert; Claude Pollard Jr.; Thomas H. McGuire
- Publisher
- John Wiley and Sons
- Year
- 1953
- Tongue
- English
- Weight
- 529 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
is the anlage for three T neoplasms of similar or identical microscopic structure. These are the retinoblastoma occurring in the retina, the medulloblastoma occurring in the cerebellum and rarely elsewhere in the encephalon, and the neuroblastoma originating in the suprarenal medulla. These three types of neoplasms arise from the medullary plate at different levels and while similar in structure they vary in their behavior. Medulloblastomas are infiltrating neoplasms that rarely produce distant metastases. Retinoblastomas metastasize widely. T h e neuroblastoma of the suprarenal medulla is apt to metastasize extensively. All these neoplasms occur in infancy and childhood and are rarely observed in adults. In this paper the clinical history and findings at necropsy are presented of a 53-yearold patient with a neuroblastoma that apparently arose from the anlage of the suprarenal medulla but outside the suprarenal gland. T h e growth was located between the right suprarenal gland and the kidney without involving either and i t produced metastases in the brain. I t is believed that this is the first such case on record.