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Neurite outgrowth and the amyloid protein precursor

✍ Scribed by Hammond, David N.


Book ID
122954263
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
233 KB
Volume
10
Category
Article
ISSN
0197-4580

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Progressive cerebral deposition of ␀-amyloid peptide either in blood vessels or around neurites is one of the most important features of Alzheimer's disease (AD). The ␀-peptide, known as A␀ or A4, is produced by proteolytic cleavage of the amyloid precursor protein (APP). Two APP processing pathways