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Neural stem cells as tools for drug discovery: novel platforms and approaches

✍ Scribed by Gorba, Thorsten; Conti, Luciano

Book ID
120405347
Publisher
Informa plc
Year
2013
Tongue
English
Weight
351 KB
Volume
8
Category
Article
ISSN
1746-0441

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## Abstract Mutational activation of RAS proteins occurs in nearly 30% of all human tumors. To date direct pharmacological inhibition of RAS oncoproteins has not been possible. As a consequence, current strategies are focusing on the development of inhibitors that target those kinases acting downst