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Neural crest ablation does not alter pulmonary vein development in the chick embryo

โœ Scribed by Phillips, Marvin T. ;Waldo, Karen ;Kirby, Margaret L.

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
840 KB
Volume
223
Category
Article
ISSN
0003-276X

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โœฆ Synopsis

Cranial neural crest, which extends from the mid-diencephalon to somite five, plays a n integral role in development of pharyngeal arch derivatives and supplies mesenchyme to the aortic arch arteries. Neural crest cells in pharyngeal arches three, four, and six migrate to the heart and are involved in aorticopulmonary and conotruncal septation. Ablation of the "cardiac" neural crest cells in chick embryos results in a variety of outflow tract anomalies, including persistent truncus arteriosus. Although other studies have shown the importance of the neural crest in the development of the cardiac outflow tract, the role of neural crest in venous development has not been established. This investigation evaluates the effect of cardiac neural crest ablation on the morphological development of the pulmonary vein. The presence of the pulmonary vein was confirmed initially at early stage 15

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Transient cranial hemorrhage does not cause depressed contractility in cardiac neural crest-ablated chick embryos
โœ Kirby, Amy D.; Wolfe, Raymond R.; Johnson, Maribeth; Leatherbury, Linda; Kirby, ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 65 KB

Ablation of cardiac neural crest results in cardiovascular malformations. Depressed ventricular contractility has been noted in cardiac neural crest-ablated embryos several hours before the time when neural crest cells would have arrived in the cardiac outflow tract and several days before the appea