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Neural control of spinal muscular atrophy in children

✍ Scribed by I. Hausmanowa-Petrusewicz; M.R. Dimitrijević


Book ID
115868573
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
121 KB
Volume
75
Category
Article
ISSN
0013-4694

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## Abstract Mutations of the survival motor neuron (SMN) gene in spinal muscular atrophy (SMA) lead to anterior horn cell death. The cause is unknown, but motor neurons depend substantially on mitochondrial oxidative phosphorylation (OxPhos) for normal function. Therefore, mitochondrial parameters