To clarify the role of neural cell adhesion molecule (NCAM) in perineural invasion, NCAM expression was studied by immunohistochemical staining in 26 cases with gallbladder cancer. In gallbladder cancer, the incidence of perineural invasion and that of positive NCAM expression was 42% and 3 1 %, res
Neural cell adhesion molecule is upregulated in nerves with prostate cancer invasion
โ Scribed by Rile Li; Thomas Wheeler; Hong Dai; Gustavo Ayala
- Book ID
- 118550122
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 327 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1532-8392
No coin nor oath required. For personal study only.
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Perineural invasion is associated with tumor spreading and an unfavorable prognosis in a variety of cancers. Recently, neural cell adhesion molecule (NCAM) has been reported to be affinitive to neural tissues, which suggests some relationship between NCAM and perineural invasion. This study was desi
## Background: Tumorigenesis and progression to metastatic disease are accompanied by changes in the expression of cell adhesion molecules (cams). normally expressed cams, such as e-cadherin, are lost, while others, i.e., icam-1, vcam-1, ncam, and e-selectin, are altered and overexpressed in progre